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Despite improvements in imaging and diagnostic procedures in critically ill patients presenting with organ failure, uncertainty often exists with regard to the exact diagnosis and a corresponding targeted therapy. Recent studies have demonstrated an error rate of up to 44% in diagnosis after autopsy [1]. The novel coronavirus disease 2019 (COVID-19)—especially the associated severe acute respiratory syndrome—led to a rush of critically ill patients to intensive care units, which were neither prepared in terms of staff and logistic demands nor in terms of specific knowledge of such a new disease. |