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Results 481-490 of 691 (Search time: 0.004 seconds).
    • Enhanced long-lived dark photon signals at lifetime frontier detectors
    Authors: Ming xuan Du; Rundong, Fang; Zuowei, Liu; Van Que, Tran;  Advisor: -;  Co-Author: - (2022)

    Long-lived particles that are present in many new physics models beyond the standard model, can be searched for in a number of newly proposed lifetime frontier experiments at the LHC. The signals of the long-lived dark photons can be significantly enhanced in a new dark photon model in which dark photons are copiously produced in the hidden radiation process. We investigate the capability of various lifetime frontier detectors in probing the parameter space of this model, including the far forward detectors FACET and FASER, the far transverse detector MATHUSLA, and the precision timing detector CMS-MTD.
    • Crystal structures of two camelid nanobodies raised against GldL, a component of the type IX secretion system from Flavobacterium johnsoniae
    Authors: T. T. N. Trinh; A. Gaubert; P. Melani; C. Cambillau; A. Roussel; P. Leone;  Advisor: -;  Co-Author: - (2021)

    GldL is an inner-membrane protein that is essential for the function of the type IX secretion system (T9SS) in Flavobacterium johnsoniae. The complex that it forms with GldM is supposed to act as a new rotary motor involved in the gliding motility of the bacterium. In the context of structural studies of GldL to gain information on the assembly and function of the T9SS, two camelid nanobodies were selected, produced and purified. Their interaction with the cytoplasmic domain of GldL was characterized and their crystal structures were solved. These nanobodies will be used as crystallization chaperones to help in the crystallization of the cytoplasmic domain of GldL and could also help to solve the structure of the complex using molecular replacement.
    • Two-dimensional viscoelastic imaging using an enhanced FDTD-AHI approach
    Authors: Tran, Quang-Huy;  Advisor: Nguyen, Thi Hoang Yen; Le, Truong Giang; Tran, Duc-Tan T;  Co-Author: - (2021)

    Ultrasound viscoelastography is a quantitative and convenient imaging model that images soft tissues based on shear waves’ propagation. Thanks to the interaction between ultrasonic waves and shear waves, the physical features of soft tissues (elasticity, viscosity) are expressed by complex shear modulus (CSM) parameters, useful information for diagnosing tissue medical states. Therefore, this paper presented a new efficient approach to estimate CSM and reconstruct the viscoelastic images.
    • Emerging roles of non‑coding RNAs in the response of rectal cancer to radiotherapy
    Authors: Ha Thi, Huyen Trang;  Advisor: Duong, Hong‑Quan; Hong, Suntaek;  Co-Author: - (2021)

    Radiotherapy (RT) followed by radical surgery is an effective standard treatment strategy for various types of cancer, including rectal cancer. The response to RT varies among patients, and the radiosensitivity of cancer cells determines the clinical outcome of patients. However, the application of RT to patients with radioresistant tumors may result in radiation‑induced toxicity without clinical benefits. Currently, there are no effective methods to predict the response to RT. The limitations of the methods currently used to evaluate tumor radiosensitivity, which are mainly based on clinical and radiological features, are low sensitivity and specificity. Non‑coding RNAs (ncRNAs) have emerged as a class of biomarkers for predicting radiosensitivity. In particular, the expression pat...