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  • Authors: Nhung Thi Trang Trinh; Hieu Quang Tran; Quyen Van Dong; Christian Cambillau; Alain Roussel; Philippe Leone;  Advisor: -;  Co-Author: - (2021)

    Porphyromonas gingivalis, the major human pathogen associated to periodontal diseases, utilizes the Bacteroidetes-specific type IX secretion system (T9SS) to export virulence factors. PorE is a periplasmic multi-domain lipoprotein associated to the outer membrane that was recently identified as essential for T9SS function. Little is known on T9SS at the structural level, and in particular its interaction with peptidoglycan. This prompted us to carry out structural studies on PorE full length as well as on its four isolated domains. Here we report the crystal structure of the C-terminal OmpA_C-like putative peptidoglycan-binding domain at 1.55?� resolution. An electron density volume was identified in the protein cleft, making it possible to build a naturally-occurring peptidoglycan ...

  • Authors: Minh Cuong Duong; Hong Trang Nguyen; Bich Thuy Duong; Minh Thuy Vu;  Advisor: -;  Co-Author: - (2021)

    Vietnam is among the few countries that were successful in the fight against the first wave of coronavirus disease 2019 (COVID-19). However, subsequent domestic outbreaks of COVID-19 continue to occur. To sharp the community education program to guarantee

  • Authors: Cuong T. Nguyen; Thao P. Trinh; Truong V. Vu;  Advisor: -;  Co-Author: - (2021)

    Sustainability requires that once reservoirs are built, they should be managed as environmentally friendly as possible. If the management policy does not achieve efficiency, there might be a man-made disaster occurred. There is a need for establishing a national strategy for developing hydrological forecasting techniques. In this study, hydrological models MARINE and SWAT were established for the Ban-Chat reservoir basin by testing performance in simulating hourly inflow during flood season for short term forecast and daily inflow for long term management respectively. Both models are set up using the same available database but they differ in terms of spatial discretization, infiltration and water redistribution representation and river flow transfer. Overall, it is argued that MAR...

  • Authors: T. Takeda; M. Kitajima; N. T. T. Huong; A. S. Setiyawan; T. Setiadi; D. T. Hung; E. Haramoto;  Advisor: -;  Co-Author: - (2021)

    This mini review describes the current status and challenges regarding institutionalisation of wastewater surveillance systems against COVID-19. Monitoring SARS-CoV-2 in wastewater has been proposed to be a potential tool to understand the actual prevalence of COVID-19 in the community, and it could be an effective approach to monitor the trend during the COVID-19 pandemic. However, challenges to institutionalise wastewater surveillance systems are still abundant and unfolding at a rapid rate given that the international understanding regarding the scientific knowledge and socio-political impacts of COVID-19 are in the developing stages. To better understand the existing challenges and bottlenecks, a comparative study between Japan, Viet Nam, and Indonesia was carried out in the pre...