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    • The adult and pediatric palliative care differences and shared issues
    Authors: Cosimo, Chelazzi; Gianluca, Villa; Iacopo, Lanini;  Advisor: -;  Co-Author: - (2023)

    Adult and pediatric palliative care (PC) share common aims and ethical principles but differ in many organizational and practical aspects. The aim of this narrative review is to analyze these differences and focus on which key aspects of pediatric palliative care could integrate adult services for a better care of suffering patients.
    • Clinical values of diaphragmatic movement in patients with chronic obstructive pulmonary disease
    Authors: Taehwa, Kim; Sungchul, Huh; Jae Heun, Chung;  Advisor: -;  Co-Author: - (2023)

    The limitation of activity due to dyspnea in chronic obstructive pulmonary disease (COPD) patients is affected by diaphragmatic dysfunction and reduced lung function. This study aimed to analyze the association between diaphragm function variables and forced expiratory volume in the first second (FEV1) and to estimate the clinical significance of diaphragm function in the correlation between COPD severity and lung function.
    • Validation of a non-invasive pressure–time index of the inspiratory muscles in spontaneously breathing newborn infants
    Authors: Theodore, Dassios; Aggeliki, Vervenioti; Sotirios, Tzifas;  Advisor: -;  Co-Author: - (2023)

    To validate the pressure–time index of the inspiratory muscles as a non-invasive index of inspiratory muscle function in spontaneously breathing infants by comparing it against the gold-standard pressure–time index of the diaphragm. Prospective observational cohort study of consecutive infants breathing unsupported in room air in a tertiary neonatal intensive care unit, studied prior to discharge from neonatal care.
    • Application of non-invasive ICP waveform analysis in acute brain injury: Intracranial Compliance Scale
    Authors: Gustavo, Frigieri; Chiara, Robba; Fábio Santana, Machado;  Advisor: -;  Co-Author: - (2023)

    Various non-invasive monitoring techniques have been developed in recent years seeking to minimize the burden that repeated imaging and invasive procedures may inflict on the journey of patients with acute brain injuries (ABI). Furthermore, the combination of these methods may theoretically enhance their predictive value for functional outcomes, as well as the detection of alterations in intracranial compliance (ICC) and intracranial hypertension [1].
    • Bleeding after endobronchial biopsy: sometimes frightening, often safe, always careful
    Authors: Saibin, Wang; Qian, Ye;  Advisor: -;  Co-Author: - (2023)

    However, it should be noted that endobronchial biopsy (EBB), which is the biopsy method used in our study [2], is different from TBLB. TBLB is usually used to collect samples of peripheral lung lesions, diffuse lesions, or infiltrative lesions around the lung, meaning that the lesions commonly receive blood supply from both bronchial and pulmonary artery. In addition, TBLB is generally performed with or without X-ray guidance, and it is usually difficult to see the lesions under the direct view of the bronchoscope. Nevertheless, in our study, lung cancer samples were collected using EBB. On the one hand, the main blood supplies to lung cancer come from the bronchial arteries [3, 4], thus, the pulmonary artery pressure has anatomically little influence with EBB-induced bleeding.
    • Diagnosis and Management of Posterior Cortical Atrophy
    Authors: Keir X. X. Yong, Yong; Jonathan, Graff-Radford; Samrah, Ahmed;  Advisor: -;  Co-Author: - (2023)

    The study aims to provide a summary of recent developments for diagnosing and managing posterior cortical atrophy (PCA). We present current efforts to improve PCA characterisation and recommendations regarding use of clinical, neuropsychological and biomarker methods in PCA diagnosis and management and highlight current knowledge gaps.