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Results 81-90 of 373 (Search time: 0.006 seconds).

No evidence for relevant impact of renal replacement therapy on clinical effect of erythromycin in critically ill patients with sepsis

Authors: Tom D. Y., Reijnders; Hessel, Peters-Sengers; Tom van der, Poll; Advisor: -; Co-Author: - (2023)

We appreciate the insightful comments by Prof. Honoré and colleagues regarding our target trial emulation on the effect of erythromycin in critically ill patients with sepsis [1, 2]. Prof. Honoré and colleagues suggest that, in theory, removal of erythromycin from the circulation by renal replacement therapy (RRT) could dilute the potential effect of erythromycin, and that it may therefore be necessary to exclude patients undergoing RRT.

Changes in upper airways microbiota in ventilator-associated pneumonia

Authors: Laura, Alagna; Leonardo, Mancabelli; Federico, Magni; Advisor: -; Co-Author: - (2023)

The role of upper airways microbiota and its association with ventilator-associated pneumonia (VAP) development in mechanically ventilated (MV) patients is unclear. Taking advantage of data collected in a prospective study aimed to assess the composition and over-time variation of upper airway microbiota in patients MV for non-pulmonary reasons, we describe upper airway microbiota characteristics among VAP and NO-VAP patients.

Real-time evaluation of the independent analgesic efficacy of dexmedetomidine

Authors: XiaoHua, Wang; SiYuan, Zhang; Chunxiu, Wang; Advisor: -; Co-Author: - (2023)

Dexmedetomidine has analgesic properties, but the intraoperative analgesic effect of dexmedetomidine is often masked by the effects of other general anaesthetics. Therefore, the degree to which it reduces intraoperative pain intensity remains unclear. The objective of this double-blind, randomised controlled trial was to evaluate the independent intraoperative analgesic efficacy of dexmedetomidine in real-time.

Monitoring of pulmonary involvement in critically ill COVID-19 patients - should lung ultrasound be preferred over CT?

Authors: Arthur W. E., Lieveld; Micah L. A., Heldeweg; Jasper, Schouwenburg; Advisor: -; Co-Author: - (2023)

It is unclear if relevant changes in pulmonary involvement in critically ill COVID-19 patients can be reliably detected by the CT severity score (CTSS) and lung ultrasound score (LUSS), or if these changes have prognostic implications. In addition, it has been argued that adding pleural abnormalities to the LUSS could improve its prognostic value.

Non-invasive assessment of Pulse Wave Transit Time (PWTT) is a poor predictor for intraoperative fluid responsiveness: a prospective observational trial (best-PWTT study)

Authors: Kimiko, Fukui; Johannes M., Wirkus; Erik K., Hartmann; Advisor: -; Co-Author: - (2023)

Aim of this study is to test the predictive value of Pulse Wave Transit Time (PWTT) for fluid responsiveness in comparison to the established fluid responsiveness parameters pulse pressure (ΔPP) and corrected flow time (FTc) during major abdominal surgery.

Intensive care drug therapy and its potential adverse effects on blood pressure and heart rate in critically ill children

Authors: Lisa Marie, Kiesel; Astrid, Bertsche; Wieland, Kiess; Advisor: -; Co-Author: - (2023)

Owing to complex treatment, critically ill children may experience alterations in their vital parameters. We investigated whether such hemodynamic alterations were temporally and causally related to drug therapy.

Influence of opioid analgesia type on circulating tumor cells in open colorectal cancer surgery (POACC-1): study protocol for a prospective randomized multicenter controlled trial

Authors: Emil, Berta; Josef, Srovnal; Petr, Dytrych; Advisor: -; Co-Author: - (2023)

Opioids and epidural analgesia are a mainstay of perioperative analgesia but their influence on cancer recurrence remains unclear. Based on retrospective data, we found that cancer recurrence following colorectal cancer surgery correlates with the number of circulating tumor cells (CTCs) in the early postoperative period. Also, morphine- but not piritramide-based postoperative analgesia increases the presence of CTCs and shortens cancer-specific survival. The influence of epidural analgesia on CTCs has not been studied yet.

Incidence of near-death experiences in patients surviving a prolonged critical illness and their long-term impact: a prospective observational study

Authors: Anne-Françoise, Rousseau; Laurence, Dams; Quentin, Massart; Advisor: -; Co-Author: - (2023)

So far, the few prospective studies on near-death experience (NDE) were carried out only in intensive care unit (ICU) patients with homogeneous aetiologies, such as cardiac arrest or trauma survivors. The aims of this 1-year prospective and monocentric study were to investigate the incidence of NDE in ICU survivors (all aetiologies) as well as factors that may affect its frequency, and to assess quality of life up to 1 year after enrolment.

Can artificial intelligence help for scientific writing?

Authors: Michele, Salvagno; Fabio Silvio, Taccone; Advisor: -; Co-Author: - (2023)

This paper discusses the use of Artificial Intelligence Chatbot in scientific writing. ChatGPT is a type of chatbot, developed by OpenAI, that uses the Generative Pre-trained Transformer (GPT) language model to understand and respond to natural language inputs. AI chatbot and ChatGPT in particular appear to be useful tools in scientific writing, assisting researchers and scientists in organizing material, generating an initial draft and/or in proofreading. There is no publication in the field of critical care medicine prepared using this approach; however, this will be a possibility in the next future.

Lung cancer in the emergency department

Authors: Jeremy R., Walder; Saadia A., Faiz; Marcelo, Sandoval; Advisor: -; Co-Author: - (2023)

Though decreasing in incidence and mortality in the USA, lung cancer remains the deadliest of all cancers. For a significant number of patients, the emergency department (ED) provides the first pivotal step in lung cancer prevention, diagnosis, and management. As screening recommendations and treatments advance, ED providers must stay up-to-date with the latest lung cancer recommendations. The purpose of this review is to identify the many ways that emergency providers may intersect with the disease spectrum of lung cancer and provide an updated array of knowledge regarding detection, management, complications, and interdisciplinary care.