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  • Authors: Gavin D., Perkins; Keith, Couper;  Advisor: -;  Co-Author: - (2023)

    The Chain of Survival highlights the effectiveness of early recognition of cardiac arrest and call for help, early cardiopulmonary resuscitation and early defibrillation. Most patients, however, remain in cardiac arrest despite these interventions. Drug treatments, particularly the use of vasopressors, have been included in resuscitation algorithms since their inception.

  • Authors: Louis A., Gomez; Qi, Shen; Kevin, Doyle;  Advisor: -;  Co-Author: - (2023)

    Impaired consciousness is common in intensive care unit (ICU) patients, and an individual’s degree of consciousness is crucial to determining their care and prognosis. However, there are no methods that continuously monitor consciousness and alert clinicians to changes. We investigated the use of physiological signals collected in the ICU to classify levels of consciousness in critically ill patients.

  • Authors: Johann, Lambeck; Christine, Steiert; Jürgen, Bardutzky;  Advisor: -;  Co-Author: - (2023)

    The main complication of intravenous application of recombinant tissue plasminogen activator (rtPA) in acute ischemic stroke is secondary intracerebral hemorrhage (sICH), which occurs in 1.7–8.8% of patients [1, 2], typically in the first 48 h following rtPA administration. It is associated with a mortality rate of up to 70%, mainly due to the mass effect of the hematoma [3].

  • Authors: Stephan, Katzenschlager; Christoph M., Simon; Patrick, Rehn;  Advisor: -;  Co-Author: - (2023)

    Acute respiratory distress syndrome (ARDS) describes a polyetiological clinical picture characterized by diffuse alveolar damage and acute respiratory failure which has a prevalence of 10% in intensive care units [1]. One factor that influences mortality is the ventilatory strategy in invasively ventilated ARDS patients. Since the ARMA trial, there has been no multicenter randomized controlled trial that has been able to assign further mortality benefit to a particular ventilatory strategy [2]. The main goals of invasive ventilation strategies are to ensure an acceptable gas exchange while preventing ventilator-induced lung injury (VILI) therefore buying time for the lung to heal [3]