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  • Authors: Simon, Bourcier; Maxime, Coutrot; Alexis, Ferré;  Advisor: -;  Co-Author: - (2023)

    Hypothyroidism is a pathological condition related to a deficiency in circulating thyroid-hormone concentrations [1]. Etiologies are mainly autoimmune thyroiditis, iodine deficiency, post-thyroidectomy or pharmacological, and central due to pituitary or hypothalamic disorders [1, 2]. Although the prevalence of overt hypothyroidism is estimated at 1–2% of the general population [3], hypothyroidism may result in a wide range of severity from subclinical hypothyroidism to exceptional life-threatening myxedema coma (MC).

  • Authors: Simon, Bourcier; Maxime, Coutrot; Alexis, Ferré;  Advisor: -;  Co-Author: - (2023)

    Severe hypothyroidism (SH) is a rare but life-threatening endocrine emergency. Only a few data are available on its management and outcomes of the most severe forms requiring ICU admission. We aimed to describe the clinical manifestations, management, and in-ICU and 6-month survival rates of these patients.