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dc.contributor.authorDamien, Roux-
dc.contributor.authorNicolas, Benichou-
dc.contributor.authorDavid, Hajage-
dc.date.accessioned2023-03-21T02:40:10Z-
dc.date.available2023-03-21T02:40:10Z-
dc.date.issued2023-
dc.identifier.urihttps://link.springer.com/article/10.1186/s13613-023-01105-0-
dc.identifier.urihttps://dlib.phenikaa-uni.edu.vn/handle/PNK/7010-
dc.descriptionCC BYvi
dc.description.abstractSepsis prognosis correlates with antibiotic adequacy at the early phase. This adequacy is dependent on antibacterial spectrum, bacterial resistance profile and antibiotic dosage. Optimal efficacy of beta-lactams mandates concentrations above the minimal inhibitory concentration (MIC) of the targeted bacteria for the longest time possible over the day. Septic acute kidney injury (AKI) is the most common AKI syndrome in ICU and often mandates renal replacement therapy (RRT) initiation. Both severe AKI and RRT may increase outside target antibiotic concentrations and ultimately alter patient’s prognosis.vi
dc.language.isoenvi
dc.publisherSpringervi
dc.subjectminimal inhibitory concentrationvi
dc.subjectacute kidney injuryvi
dc.titleImpact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trialvi
dc.typeBookvi
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