Item Infomation
Title: | Bioinspired surface functionalization of biodegradable mesoporous silica nanoparticles for enhanced lubrication and drug release |
Authors: | Xiaowei, Mao Kexin, Chen Yanlong, Zhao |
Issue Date: | 2022 |
Publisher: | Springer |
Abstract: | Osteoarthritis is associated with the significantly increased friction of the joint, which results in progressive and irreversible damage to the articular cartilage. A synergistic therapy integrating lubrication enhancement and drug delivery is recently proposed for the treatment of early-stage osteoarthritis. In the present study, bioinspired by the self-adhesion performance of mussels and super-lubrication property of articular cartilages, a biomimetic self-adhesive dopamine methacrylamide—poly(2-methacryloyloxyethyl phosphorylcholine) (DMA—MPC) copolymer was designed and synthesized via free radical polymerization. |
Description: | CC BY |
URI: | https://link.springer.com/article/10.1007/s40544-022-0648-z https://dlib.phenikaa-uni.edu.vn/handle/PNK/7948 |
Appears in Collections | OER - Kỹ thuật điện; Điện tử - Viễn thông |
ABSTRACTS VIEWS
29
FULLTEXT VIEWS
1
Files in This Item: