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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Ohnishi, Chie | - |
| dc.contributor.author | Ohnishi, Takashi | - |
| dc.contributor.author | Ntiamoah, Peter | - |
| dc.date.accessioned | 2023-09-18T04:10:57Z | - |
| dc.date.available | 2023-09-18T04:10:57Z | - |
| dc.date.issued | 2023 | - |
| dc.identifier.uri | https://link.springer.com/article/10.1186/s42649-023-00091-8 | - |
| dc.identifier.uri | https://dlib.phenikaa-uni.edu.vn/handle/PNK/9064 | - |
| dc.description | CC-BY | vi |
| dc.description.abstract | In the evaluation of human epidermal growth factor receptor 2 (HER2) immunohistochemistry (IHC) — one of the standard biomarkers for breast cancer— visual assessment is laborious and subjective. Image analysis using whole slide image (WSI) could produce more consistent results; however, color variability in WSIs due to the choice of stain and scanning processes may impact image analysis. We therefore developed a calibration protocol to diminish the staining and scanning variations of WSI using two calibrator slides. The IHC calibrator slide (IHC-CS) contains peptide-coated microbeads with different concentrations. The color distribution obtained from the WSI of stained IHC-CS reflects the staining process and scanner characteristics. A color chart slide (CCS) is also useful for calibrating the color variation due to the scanner. | vi |
| dc.language.iso | en | vi |
| dc.publisher | Springer | vi |
| dc.subject | IHC-CS | vi |
| dc.subject | CCS | vi |
| dc.title | Standardizing HER2 immunohistochemistry assessment: calibration of color and intensity variation in whole slide imaging caused by staining and scanning | vi |
| dc.type | Book | vi |
| Appears in Collections | ||
| OER - Khoa học Vật liệu, Ứng dụng | ||
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