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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Salim, Elsayed I. | - |
| dc.contributor.author | Mahfouz, Magdy E. | - |
| dc.contributor.author | Eltonouby, Eman A. | - |
| dc.date.accessioned | 2023-10-09T03:36:37Z | - |
| dc.date.available | 2023-10-09T03:36:37Z | - |
| dc.date.issued | 2023 | - |
| dc.identifier.uri | https://link.springer.com/article/10.1186/s12645-023-00229-z | - |
| dc.identifier.uri | https://dlib.phenikaa-uni.edu.vn/handle/PNK/9508 | - |
| dc.description | CC-BY | vi |
| dc.description.abstract | Bee pollen extract (BPE)-based polymer nanoparticles (BPENP) were fabricated using bovine serum albumin (BSA) and targeted with folic acid and were further characterized. Mice groups are: Group 1 received saline, whereas Groups 2, 3, 4, 5, and 6 received a single dose of urethane, followed by weekly injections of butylated hydroxy-toluene (BHT). After the BHT injection, the mice in Groups 3, 4, 5, and 6 received BPE, Avastin, BPENP, and BPENP + Avastin, respectively. The number and size of tumors were decreased in Group 6 compared to those in the other groups. The ratios of early and late apoptotic cells in Groups 3, 4, 5, and 6 (42.8%, 41.4%, 26.2%, and 45.4%, respectively) were higher than that in the untreated group. The PCNA-labeling indexes (LI)% in tissues and lesions from Group 6 were lower than those in the other groups; on the other hand, the Caspase-3 LI (%) was higher than those in the other groups. | vi |
| dc.language.iso | en | vi |
| dc.publisher | Springer | vi |
| dc.subject | BPE | vi |
| dc.subject | BPENP | vi |
| dc.title | Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo | vi |
| dc.type | Book | vi |
| Appears in Collections | OER - Khoa học Vật liệu, Ứng dụng | |
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