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Browsing by Author Aline H. de, Nooijer

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    • Complement activation in severely ill patients with sepsis: no relationship with inflammation and disease severity
    Authors: Aline H. de, Nooijer; Antigone, Kotsaki; Eleftheria, Kranidioti;  Advisor: -;  Co-Author: - (2023)

    Sepsis is characterized by a dysregulated immune response to infection. The complement system plays an important role in the host defence to pathogens. However, exaggerated complement activation might contribute to a hyperinflammatory state. The interplay between complement activation and inflammation in relationship with adverse outcomes in sepsis patients is unclear.