Item Infomation
| Title: | Novel 4-Oxoquinazoline-Based N-Hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis, and Biological Evaluation |
| Authors: | Duong T. Anh Pham-The Hai Le D. Huy Hoang B. Ngoc Trinh T. M. Ngoc Do T. M. Dung Eun J. Park In K. Song Jong S. Kang Joo-Hee Kwon Truong T. Tung Sang-Bae Han Nguyen-Hai Nam |
| Issue Date: | 2021 |
| Publisher: | American Chemical Society |
| Abstract: | Two series of novel 4-oxoquinazoline-based N-hydroxypropenamides (9a–m and 10a–m) were designed, synthesized, and evaluated for their inhibitory and cytotoxicity activities against histone deacetylase (HDAC). The compounds showed good to potent HDAC inhib |
| URI: | https://pubs.acs.org/doi/abs/10.1021/acsomega.0c05870 https://dlib.phenikaa-uni.edu.vn/handle/PNK/2748 |
| Appears in Collections | Bài báo khoa học |
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