Item Infomation
| Title: |
| Novel 4-Oxoquinazoline-Based N-Hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis, and Biological Evaluation |
| Authors: |
| Duong T. Anh Pham-The Hai Le D. Huy Hoang B. Ngoc Trinh T. M. Ngoc Do T. M. Dung Eun J. Park In K. Song Jong S. Kang Joo-Hee Kwon Truong T. Tung Sang-Bae Han Nguyen-Hai Nam |
| Issue Date: |
| 2021 |
| Publisher: |
| American Chemical Society |
| Abstract: |
| Two series of novel 4-oxoquinazoline-based N-hydroxypropenamides (9a–m and 10a–m) were designed, synthesized, and evaluated for their inhibitory and cytotoxicity activities against histone deacetylase (HDAC). The compounds showed good to potent HDAC inhib |
| URI: |
| https://pubs.acs.org/doi/abs/10.1021/acsomega.0c05870 https://dlib.phenikaa-uni.edu.vn/handle/PNK/2748 |
| Appears in Collections |
| Bài báo khoa học |
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