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Results 221-230 of 373 (Search time: 0.004 seconds).

Time Course and Clinical Significance of Hematoma Expansion in Moderate-to-Severe Traumatic Brain Injury: An Observational Cohort Study

Authors: Alexander, Fletcher-Sandersjöö; Charles, Tatter; Jonathan, Tjerkaski; Advisor: -; Co-Author: - (2023)

Preventing intracranial hematoma expansion has been advertised as a possible treatment opportunity in traumatic brain injury (TBI). However, the time course of hematoma expansion, and whether the expansion affects outcome, remains poorly understood. In light of this, the aim of this study was to use 3D volume rendering to determine how traumatic intracranial hematomas expand over time and evaluate its impact on outcome.

Changes of cardiac output and velocity time integral in blood return at the end of renal replacement therapy predict fluid responsiveness in critically Ill patients with acute circulatory failure

Authors: Daozheng, Huang; Jie, Ma; Shouhong, Wang; Advisor: -; Co-Author: - (2023)

To observe if blood return, also defined as the blood infusion test (BIT) could predict fluid responsiveness in critically ill patients with acute circulatory failure and renal replacement therapy (RRT).

The influence of inter-hospital transfers on mortality in severely injured patients

Authors: Job F., Waalwijk; Robin D., Lokerman; Rogier van der, Sluijs; Advisor: -; Co-Author: - (2023)

The importance of treating severely injured patients in higher-level trauma centers is undisputable. However, it is uncertain whether severely injured patients that were initially transported to a lower-level trauma center (i.e., undertriage) benefit from being transferred to a higher-level trauma center.

Is hospital volume related to quality of hip fracture care? Analysis of 43,538 patients and 68 hospitals from the Dutch Hip Fracture Audit

Authors: Franka S., Würdemann; Erik W. van, Zwet; Pieta, Krijnen; Advisor: -; Co-Author: - (2023)

Evidence for a hospital volume–outcome relationship in hip fracture surgery is inconclusive. This study aimed to analyze the association between hospital volume as a continuous parameter and several processes and outcomes of hip fracture care.

A well-known but rarely seen interaction: propofol with lignocaine

Authors: Ashwini, Reddy; Sanjay, Kumar; Shalvi, Mahajan; Advisor: -; Co-Author: - (2023)

Propofol is considered an excellent intravenous anesthetic agent. However, a 30–70% incidence of pain associated with its injection is a significant source of patient discontent. Injection pain and discomfort rank as the sixth most crucial perioperative issue (Desousa 2016). Several techniques have been employed to reduce injection discomfort, including the use of the forearm and antecubital veins, freezing or warming the injectate, and aspirating blood before injection. Pre-treatment or contemporaneous administration of thiopentone, pethidine, fentanyl, dexamethasone, nitroglycerine, ketorolac, and local anesthetics has also been considered.

Early total care or damage control orthopaedics for major fractures ? Results of propensity score matching for early definitive versus early temporary fixation based on data from the trauma registry of the German Trauma Society (TraumaRegister DGU®)

Authors: Falk von, Lübken; Sascha, Prause; Patricia, Lang; Advisor: -; Co-Author: - (2023)

Damage control orthopaedics (DCO) und early total care (ETC) are well-established strategies for managing severely injured patients. There is no definitive evidence of the superiority of DCO over ETC in polytrauma patients. We conducted this study to assess the probability of a polytraumatised patient undergoing DCO. In addition, the effect of DCO on complications and mortality was investigated.

Resuscitation with whole blood or blood components improves survival and lessens the pathophysiological burden of trauma and haemorrhagic shock in a pre-clinical porcine model

Authors: Sarah Ann, Watts; Jason Edward, Smith; Thomas, Woolley; Advisor: -; Co-Author: - (2023)

In military trauma, disaster medicine, and casualties injured in remote locations, times to advanced medical and surgical treatment are often prolonged, potentially reducing survival and increasing morbidity. Since resuscitation with blood/blood components improves survival over short pre-surgical times, this study aimed to evaluate the quality of resuscitation afforded by blood/blood products or crystalloid resuscitation over extended ‘pre-hospital’ timelines in a porcine model of militarily relevant traumatic haemorrhagic shock.

Ratio of carbon dioxide veno-arterial difference to oxygen arterial-venous difference is not associated with lactate decrease after fluid bolus in critically ill patients with hyperlactatemia: results from a prospective observational study

Authors: Keitiane, Kaefer; Charalampos, Pierrakos; Thomas, Nguyen; Advisor: -; Co-Author: - (2023)

High ratio of the carbon dioxide veno-arterial difference to the oxygen arterial-venous difference (PvaCO2/CavO2) is associated with fluid bolus (FB) induced increase in oxygen consumption (VO2). This study investigated whether PvaCO2/CavO2 was associated with decreases in blood-lactate levels FB in critically ill patients with hyperlactatemia.

Pulmonary gas exchange evaluated by machine learning a computer simulation

Authors: Thomas J., Morgan; Adrian N., Langley; Robin D. C., Barrett; Advisor: -; Co-Author: - (2023)

Using computer simulation we investigated whether machine learning (ML) analysis of selected ICU monitoring data can quantify pulmonary gas exchange in multi-compartment format. A 21 compartment ventilation/perfusion (V/Q) model of pulmonary blood flow processed 34,551 combinations of cardiac output, hemoglobin concentration, standard P50, base excess, VO2 and VCO2 plus three model-defining parameters: shunt, log SD and mean V/Q.

A deep learning model for the classification of atrial fibrillation in critically ill patients

Authors: Brian, Chen; David M., Maslove; Jeffrey D., Curran; Advisor: -; Co-Author: - (2023)

Atrial fibrillation (AF) is the most common cardiac arrhythmia in the intensive care unit and is associated with increased morbidity and mortality. New-onset atrial fibrillation (NOAF) is often initially paroxysmal and fleeting, making it difficult to diagnose, and therefore difficult to understand the true burden of disease. Automated algorithms to detect AF in the ICU have been advocated as a means to better quantify its true burden.