Thông tin tài liệu
Nhan đề : | Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development |
Tác giả : | Ishraq U., Ahmed Helen M., Byrne Mary R., Myerscough |
Năm xuất bản : | 2023 |
Nhà xuất bản : | Springer |
Tóm tắt : | Atherosclerosis is an inflammatory disease characterised by the formation of plaques, which are deposits of lipids and cholesterol-laden macrophages that form in the artery wall. The inflammation is often non-resolving, due in large part to changes in normal macrophage anti-inflammatory behaviour that are induced by the toxic plaque microenvironment. These changes include higher death rates, defective efferocytic uptake of dead cells, and reduced rates of emigration. We develop a free boundary multiphase model for early atherosclerotic plaques, and we use it to investigate the effects of impaired macrophage anti-inflammatory behaviour on plaque structure and growth. |
Mô tả: | CC BY |
URI: | https://link.springer.com/article/10.1007/s11538-023-01142-7 https://dlib.phenikaa-uni.edu.vn/handle/PNK/7479 |
Bộ sưu tập | OER - Khoa học Tự nhiên |
XEM MÔ TẢ
79
XEM TOÀN VĂN
29
Danh sách tệp tin đính kèm: