Thông tin tài liệu
Nhan đề : | Enhanced supply of acetyl-CoA by exogenous pantothenate kinase promotes synthesis of poly(3-hydroxybutyrate) |
Tác giả : | Hirotaka, Kudo Sho, Ono Kenta, Abe |
Năm xuất bản : | 2023 |
Nhà xuất bản : | Springer |
Tóm tắt : | Coenzyme A (CoA) is a carrier of acyl groups. This cofactor is synthesized from pantothenic acid in five steps. The phosphorylation of pantothenate is catalyzed by pantothenate kinase (CoaA), which is a key step in the CoA biosynthetic pathway. To determine whether the enhancement of the CoA biosynthetic pathway is effective for producing useful substances, the effect of elevated acetyl-CoA levels resulting from the introduction of the exogenous coaA gene on poly(3-hydroxybutyrate) [P(3HB)] synthesis was determined in Escherichia coli, which express the genes necessary for cyanobacterial polyhydroxyalkanoate synthesis (phaABEC). |
Mô tả: | CC BY |
URI: | https://link.springer.com/article/10.1186/s12934-023-02083-5 https://dlib.phenikaa-uni.edu.vn/handle/PNK/8177 |
Bộ sưu tập | OER - Khoa học Tự nhiên |
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