Thông tin tài liệu


Nhan đề : 
Green synthesis of oncolytic Newcastle disease virus-loaded thiolated chitosan nanoformulation for CD44 targeted delivery and sustained release of virus in cervical cancer xenografts
Tác giả : 
Kousar, Kousain
Naseer, Faiza
Abduh, Maisa S.
Năm xuất bản : 
2023
Nhà xuất bản : 
Springer
Tóm tắt : 
Newcastle disease virus (NDV) Lasota strain has proven oncolytic activity. One shortcoming associated with this treatment modality is the immune neutralization of the virus in body, mediated by natural killer cells and macrophages. This study aims at encapsulating the oncolytic virus in thiolated chitosan nanoparticles, surface functionalized with hyaluronic acid for CD44 targeted delivery and sustained release of NDV in cervical cancer tumors. These nanoparticles were tested for oncolytic potential in HeLa cells and cervical cancer xenograft model.
Mô tả: 
CC-BY
URI: 
https://link.springer.com/article/10.1186/s12645-023-00220-8
https://dlib.phenikaa-uni.edu.vn/handle/PNK/8949
Bộ sưu tập
OER - Khoa học Vật liệu, Ứng dụng
XEM MÔ TẢ

18

XEM TOÀN VĂN

2

Danh sách tệp tin đính kèm: