BROWSE

Author Profile

Browsing by Author Young-Woo Kim

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:  
Showing results [1 - 1] / 1
    • Stabilization of Single Turn Polyproline II Helices via Macrocyclic Hydrocarbon Staples
    Authors: Huy X. Luong; Young-Woo Kim;  Advisor: -;  Co-Author: - (2020)

    Polyproline II helix (PPII) is one of the secondary structures in proteins that play an important role in various biological processes. In this study, we have developed a new macrocyclization strategy that efficiently reinforces a model tetrapeptide into a PPII structure. We also elucidated some relationships between structural features and PPII stability in this model. This new macrocyclic stapling strategy can serve as a useful chemical tool to manipulate the PPII structure for various applications.