Item Infomation
Title: |
Antimicrobial Properties of Distichochlamys citrea M.F. Newman Rhizome n -Hexane Extract against Streptococcus pyogenes : Experimental Evidences and Computational Screening |
Authors: |
Dr. Nguyen Van Hue Dr. To Dao Cuong Dr. Phan Tu Quy |
Issue Date: |
2022 |
Publisher: |
John Wiley & Sons |
Abstract: |
Distichochlamys citrea is an endemic plant species found only in Vietnam, known by folk medicine as a natural antibiotic source. Experimental evidences and computational validation on bioactivity of Distichochlamys citrea M.F. Newman rhizome n-hexane extract against Streptococcus pyogenes were carried out. Experiments found twenty-one bioactive components in the n-hexane extract, which altogether exhibits an overall antibiotic activity of significance against the bacterium; Computations suggested a mechanism based on inhibition of S-ribosylhomocysteine lyase structure. Its biocompatibility and pharmacology were also predicted. |
URI: |
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.202200680 https://dlib.phenikaa-uni.edu.vn/handle/PNK/5976 |
Appears in Collections |
Bài báo khoa học |
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