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Nhan đề : 
Antimicrobial Properties of Distichochlamys citrea M.F. Newman Rhizome n -Hexane Extract against Streptococcus pyogenes : Experimental Evidences and Computational Screening
Tác giả : 
Dr. Nguyen Van Hue
Dr. To Dao Cuong
Dr. Phan Tu Quy
Năm xuất bản : 
2022
Nhà xuất bản : 
John Wiley & Sons
Tóm tắt : 
Distichochlamys citrea is an endemic plant species found only in Vietnam, known by folk medicine as a natural antibiotic source. Experimental evidences and computational validation on bioactivity of Distichochlamys citrea M.F. Newman rhizome n-hexane extract against Streptococcus pyogenes were carried out. Experiments found twenty-one bioactive components in the n-hexane extract, which altogether exhibits an overall antibiotic activity of significance against the bacterium; Computations suggested a mechanism based on inhibition of S-ribosylhomocysteine lyase structure. Its biocompatibility and pharmacology were also predicted.
URI: 
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/slct.202200680
https://dlib.phenikaa-uni.edu.vn/handle/PNK/5976
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