Item Infomation
| Title: |
| Elevated free interleukin-18 associated with severity and mortality in prospective cohort study of 206 hospitalised COVID-19 patients |
| Authors: |
| Syed M. T., Nasser Anas A., Rana Rainer, Doffinger |
| Issue Date: |
| 2023 |
| Publisher: |
| Springer |
| Abstract: |
| Divergence between deterioration to life-threatening COVID-19 or clinical improvement occurs for most within the first 14 days of symptoms. Life-threatening COVID-19 shares clinical similarities with Macrophage Activation Syndrome, which can be driven by elevated Free Interleukin-18 (IL-18) due to failure of negative-feedback release of IL-18 binding protein (IL-18bp). We, therefore, designed a prospective, longitudinal cohort study to examine IL-18 negative-feedback control in relation to COVID-19 severity and mortality from symptom day 15 onwards. |
| URI: |
| https://link.springer.com/article/10.1186/s40635-022-00488-x https://dlib.phenikaa-uni.edu.vn/handle/PNK/7012 |
| Appears in Collections |
| OER- Y học- Điều dưỡng |
ABSTRACTS VIEWS
22
FULLTEXT VIEWS
8
Files in This Item: