Thông tin tài liệu


Nhan đề : 
NARall: a novel tool for reconstruction of the all-atom structure of nucleic acids from heavily coarse-grained model
Tác giả : 
Łukasz, Golon
Adam K., Sieradzan
Năm xuất bản : 
2022
Nhà xuất bản : 
Springer
Tóm tắt : 
Nucleic acids are one of the most important cellular components. These molecules have been studied both experimentally and theoretically. As all-atom simulations are still limited to short time scales, coarse-grain modeling allows to study of those molecules on a longer time scale. Nucleic-Acid united RESidue (NARES-2P) is a low-resolution coarse-grained model with two centers of interaction per repeating unit. It has been successfully applied to study DNA self-assembly and telomeric properties. This force field enables the study of nucleic acids Behavior on a long time scale but lacks atomistic details. In this article, we present new software to reconstruct atomistic details from the NARES-2P model. It has been applied to RNA pseudoknot, nucleic acid four-way junction, G-quadruplex and DNA duplex converted to NARES-2P model and back. Moreover, it was applied to DNA structure folded and self-assembled with NARES-2P.
Mô tả: 
CC BY
URI: 
https://link.springer.com/article/10.1007/s11696-022-02634-x
https://dlib.phenikaa-uni.edu.vn/handle/PNK/8157
Bộ sưu tập
OER - Khoa học Tự nhiên
XEM MÔ TẢ

26

XEM TOÀN VĂN

28

Danh sách tệp tin đính kèm: